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High Cholesterol

A Summary

by: George Pararas-Carayannis, Ph.D.*

(Excerpts from summary prepared under contract for the ReGenesis Medical Center/ Dec 2000)

* Disclaimer - I am not a medical doctor. All material provided at this website is for informational purposes only. Readers are encouraged to confirm the information contained herein with other sources. Patients and consumers should review the information carefully with their professional health care provider. The information is not intended to replace medical advice offered by physicians. I will not be liable for any direct, indirect, consequential, special, exemplary, or other damages arising therefrom.


Cholesterol is a vital component of the blood and body organs, and is present in every body cell. About 17% by weight of the human brain is cholesterol. There are many misconceptions about the function of cholesterol in the body and, in particular, the significance of a high cholesterol concentration in the blood. High blood cholesterol and hypertension arise from the same ultimate condition: an excess flux of free radicals in the body.

Significance of Cholesterol in the Human Body

Cholesterol has many functions and is of great significance in the human body. However, its most important purpose is the absorbion of excess oxidising free radicals. Only a small proportion of the cholesterol in the body arises from diet; most is synthesised in the liver. Cholesterol is produced in sufficient quantity to meet the body's needs at any given time. The concentration of cholesterol in the blood increases with the degree of oxidation arising from the flux of free radicals. That in turn is brought about largely by the catalytic effect on free radical generation resulting from the presence of certain heavy metals in the body.

This free radical generation increases as the loading of the various heavy metals in the body increases. Thus, as people age and accumulate heavy metals in their bodies, the generation of cholesterol necessarily increases to counteract the damaging effects of the additional flux of the free radicals. Furthermore, some of this cholesterol, acting as an antioxidant, is converted to oxycholesterol by the oxidising action of free radicals.

Significance of High Cholesterol Measurements

It is important to realise that analysis of blood for cholesterol does not measure solely cholesterol, but rather the aggregate of cholesterol and oxycholesterol. Therefore, this analytical figure always over-states the actual cholesterol concentration.

There is an additional factor which can increase blood cholesterol level. Much of the cholesterol in the body is transported (as either cholesterol or esters of cholesterol) by complex compounds containing unsaturated fats (lipids). Unsaturated carbon chains are particularly prone to lysis (break up) at the double bonds, resulting in the formation of oxidised end products (aldehydes) and the destruction of the lipid/cholesterol complex. This destruction releases free cholesterol into the bloodstream, thereby increasing the blood cholesterol concentration.

Relationship of High Blood Cholesterol to Cardio-Vascular Disease

Epidemiological studies have found that patients exhibiting a high cholesterol level in their blood (in fact, cholesterol plus oxycholesterol) are prone to serious cardio-vascular disease.

Frequently the high cholesterol level itself is blamed for the cardiovascular condition; whereas in fact this level is an indicator of the presence in the body of the chemical state (free radical activity) which causes such diseases as atherosclerosis, high blood pressure, coronary artery obstruction, etc.

Not surprisingly, this misconception about the significance of a high cholesterol level in the blood has led to the development of drugs designed solely to reduce blood cholesterol level; whereas in fact the culprit is not cholesterol but rather free radicals which damage the arterial system.

It cannot be denied, of course, that drug-induced reduction of blood cholesterol has benefited patients at risk of coronary heart disease. But despite the plethora of such drugs now available and the fact that some of these (at least) achieve a lowering of cholesterol, the overall impact of such drug therapy on the incidence of coronary heart disease has not been convincing.

Conventional Treatment for High blood Cholesterol

High blood cholesterol and hypertension frequently occur in conjunction, and multi-drug therapy is often prescribed to deal with these parallel conditions. The flux of free radicals can be neutralised by means of antioxidant drugs, but these have only a temporary effect.

Alternative treatment of High Blood Cholesterol

A high cholesterol level in the blood is an almost certain indicator of the need to eliminate heavy metals from the body. Therefore, the most effective means to treat high blood cholesterol is to treat the cause rather than the symptoms. Free radicals can be eliminated with intravenous EDTA chelation therapy and certain vitamins.

By reducing heavy metal concentration and the consequent reduced free radical activity, the body requires less cholesterol (and other anti-oxidants) to maintain health; the blood cholesterol level falls; and less oxycholesterol is generated. Therefore with chelation therapy, the total blood cholesterol level is steadily reduced by natural means. An additional benefit is the reduction of hypertension.

Reference on High Blood Cholesterol

There is extensive literature on cholesterol and the biochemistry involved is extensive. For a modern comprehensive explanation, reference is made to Halstead and Rozema, "The Scientific Basis of EDTA Chelation" Therapy (2nd ed, 1997) (358 references).

Miscellaneous Summaries on Chronic Illnesses

heart disease | | stroke | diabetes | | high blood pressure | | high cholesterol | | Alzheimer's | | Parkinson's | | arthritis | | chronic fatigue | | poor circulation | | brain injury | | multiple sclerosis | | cerebral palsy | | life extension | | memory loss |

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